Showing posts with label Genotype. Show all posts
Showing posts with label Genotype. Show all posts

Monday, 27 May 2013

Bloody confusion!

We are back again! Sorry for the delay. Let me compensate you with a very useful explanation about blood groups and compatibility. The eternal confusion. Am I universal receptor? Who can donate blood to who?

There exist two different human blood group systems -actually there are 32, but those two are the most important ones-, ABO and Rh antigen. 

First of all, all of you should know that the dominance in ABO group is A and B co-dominant and O recessive. It means that if we have AA or AO genotype, the phenotype will be A, if we have BB or BO the phenotype will be B, with OO we have O, and with AB the phenotype is AB.
In case of Rh we have positive (+) or negative (-) genotype, the positive is dominant and the negative recessive.

Knowing that, now... who can donate to who? Here there is a very clear table about that:

Sunday, 28 April 2013

Slight differences

Let's start with general genetics: "What is DNA and what is for?" and "How could we be apparently so different among us but at the same time the same species?"

For answering the first question we will start with the Central Dogma of Molecular Biology:


The DNA is our particular library, essential for life. We have all the necessary information encoded in a combination of four nucleotides (A, T, G and C). This library has hundreds of books, which we are going to call RNA. We have a lot of different kinds of RNA, which maybe is boring and not what you are looking for at this blog. So let's say that this RNA should be translated into proteins to be useful for a cell. These proteins will work independently or as a subunit of a big complex to make what is required.

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